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KMID : 0355220130380040313
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Journal of Korean Academy Oral Medicine
2013 Volume.38 No. 4 p.313 ~ p.318
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Review about effects of sleep disturbances on Burning mouth syndrome
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Lim Hyun-Dae
Lee You-Mee
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Abstract
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The aim of this study was to the relationship between sleep disturbances and Burning mouth syndrome(BMS). BMS presents as a chronic burning sensation in the oral mucous membrane that is frequently associated with sleep disturbances. BMS is considered neuropathic pain condition with dysfunction of small diameter afferent sensory fiber. A review of the studies reveals, BMS suggested peripheral and cental nervous system changes. Sleep disruption or Rem sleep deprivation cause an inhibition of opioid protein synthesis and a reduced affinity of μ and δ opioid receptors. Let me say that sleep disturbances suggest a risk factor For BMS and support to evaluate as a part of BMS treatment. Further study will be required to ascertain the relationship between distruption of sleep continuity or Rem sleep deprivation and BMS and the evidence of altered neurochemical degeneration of BMS.
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KEYWORD
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Sleep disturbances, Rem sleep deprivation, Neuropathic pain, Burning mouth syndrome
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